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Houston is the fourth-largest metropolitan area within the United States and a prime outdoor advertising spot. Houston is home to the second-highest number of Fortune 500 headquarters, as in addition to several universities, including University of Houston, Texas Southern University and Rice University. Utilize BillboardsIn to locate advertising space on the I-610 highway, which runs through downtown, as well as the I-10 and I-69 that directly pass through it. Houston has two major airports, IAH and HOU, and an extensive transit system consisting of buses and light rail which offer great advertising opportunities.